Rheumatoid Arthritis

Rheumatoid arthritis is an inflammatory disorder which can affect your joints. In many people, this condition leads to damage different body systems, including eyes, heart, skin, blood vessels and lungs. This is an autoimmune disorder in which your immune system mistakenly attacks the host body’s tissue. It mainly affects the lining of your joints that causes a painful swelling in the bone and eventually result in joint deformation. This inflammation also damages the other part of your body. In order to understand the mechanism of rheumatoid arthritis, you will surely know about your immune system. The immune system work as a complex organization of antibodies and cells which are designed to find and destroy the invaders of your body, particularly in the case of infection.

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rheumatoid arthritis

Patients having autoimmune diseases have immune cells and antibodies in their bloodstream which target host body tissue. The cells can be associated with inflammation. While the inflammatory arthritis and inflammation around joints and tissues are characterized as main features of rheumatoid arthritis.

In this disease, the other organs of the body also infected and get injured. It can affect multiple parts of the body, so this disease regarded as a systemic illness (rheumatoid disease). This is a type of classic rheumatic disease. It usually starts at the age of 16 years and known as juvenile idiopathic arthritis or juvenile rheumatoid arthritis. The reason of the rheumatoid arthritis is still unknown.

Infections Risk

The infectious agent may be bacteria, fungi and viruses, but none of them proven as main causative agent. The reason of this disease is a very active area under research throughout the world. It is thought that, the tendency to induce rheumatoid arthritis may be inherited genetically. Certain genes have been involved, which increase the risk of getting the disease.

It is also suspected that environmental factors or certain infections might increase the infection that triggers the activation of the host immune system. Then, the misdirected immune system destroys the body’s own cells and tissues. This situation causes the inflammation in various organs such as eyes or lungs and especially in joints.

Environmental factors

Environmental factors play a vital role in the course duration of rheumatoid arthritis. For example, many researchers have reported that chronic periodontal disease, exposure to silica minerals and smoking tobacco increase the risk of inducing disease. There are also many theories which explains the main causative agent of the disease, but the gut bacteria might trigger the duration of rheumatoid arthritis in a susceptible person. But, no specific microorganism has been identified as a definite cause of the disease.

Symptoms of Rheumatoid Arthritis

The symptoms of the rheumatoid arthritis are variable and depends on the degree of inflammation in tissues. The disease is in active form when the tissues and cells become inflamed. Inactivity of the disease might occur with treatment or spontaneously. During remission, the disease symptoms disappear and people feel well. But, when the disease becomes active again symptoms return. This situation is known as a flare. Permanent treatment of this disease is not introduced yet, but research has been carried out to show the actual reason of this disease.

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